Evaluation of DNA Intramolecular Interactions for Nucleosome Positioning in Yeast
Michael Fernandez (firstname.lastname@example.org)
Satoshi Fujii (email@example.com)
Hidetoshi Kono (firstname.lastname@example.org)
Akinori Sarai (email@example.com)
Department of Bioscience and Bioinformatics, Kyushu Institute of
Technology (KIT), Iizuka, 820-8502, Japan.
 Computational Biology Group, Japan Atomic Energy Agency, Kyoto, 619-0215, Japan
We calculated intramolecular interaction energies of DNA by threading DNA sequences around crystal structures of nucleosomes. The strength of the intramolecular energy oscillations at frequency ~10 bps for dinucleotides was in agreement with previous nucleosome models. The intramolecular energy calculated along yeast genome positively correlated with nucleosome positioning experimentally measured.
Japanese Society for Bioinformatics