In 2001 Program Officers from the NSF and the DeutscheForschungsgemeinschaft (DFG) met with Charles DeLisi from Boston University and Reinhart Heinrich from Humboldt University in Berlin todiscuss collaborative education and research opportunities for graduatestudents. Among the ideas discussed was an annual workshop, to be heldon alternate years in Germany and Boston, at which students from eachcountry would present full length talks to their counterparts ad programfaculty. Soon after the meeting, NSF and DFG provided funds, and thefirst meeting was held in Berlin, in Aug 2001. In 2003 we invited KyotoUniversity and the University of Tokyo to join us, under the sponsorshipof the Japanese Ministry of Education. In 2003, we also beganpublishing the proceedings in Genome Informatics.
This issue of Genome Informatics contains twenty-two peer reviewed papers presented at the 6th International Workshop on Bioinformatics and Systems Biology, which was held in Boston, from 24-26 July. Like past issues devoted to the conference, this issue is unusual in the range of scientific approaches to current computationally addressable questions in the systems biology of the cell. All papers are student authored, with contributions from the University of Tokyo, Kyoto University, Humboldt University, the Free University of Berlin, the Max Delbruick Center for Molecular Medicine, the Hahn-Meitner Institute, the Max Planck Institute for Molecular Genetics, and Boston University. Electronic versions of the papers are freely available from the Japanese Society for Bioinformatics (
As with all complex international meetings, this student focused meeting wouldn't have been possible without the contributions of numerous faculty and staff. We especially wish to thank the scientific committee who oversaw manuscript selection and editing: Tatsuya Akutsu, Hiroshi Mamitsuka, Susumu Goto, Keiichi Kuma, Satoru Miyano, Hermann-Georg Holzhütter, Martin Vingron, Thomas Höfer, Gary Benson and Zhiping Weng. Finally we the admisntarive logistics in Boston was conducted with extreme efficiency by Caroline Lyman and her assistant, Laura Mullen. We are deeply indebted to all.

Charles DeLisi
Minoru Kanehisa
Reinhart Heinrich
Program Committee